Unraveling The Enigmatic Replication Mechanism Of Prions
Prions, enigmatic infectious agents devoid of genetic material, replicate via a unique mechanism. Healthy PrP^C proteins, present in normal cells, misfold into abnormal PrP^Sc. This misfolding initiates a chain reaction, converting more PrP^C into PrP^Sc, leading to the accumulation of amyloid plaques. These plaques disrupt normal brain function, causing fatal neurodegenerative disorders like Creutzfeldt-Jakob disease….