Unveiling The Endoplasmic Reticulum’s Dual Role: Providing Mechanical Support And Beyond
The endoplasmic reticulum (ER) provides mechanical support by fostering proper protein folding and quality control through protein disulfide bond formation and molecular chaperones. Disulfide bonds enhance protein stability, while chaperones prevent misfolding and promote correct folding. Protein glycosylation, mediated by lectins, facilitates ER retention and export to ensure only properly folded proteins exit the ER….